Prenatally diagnosed sacrococcygeal teratoma: a unique expression of trisomy 1q

Autor:	J R, Wax, P, Benn, J D, Steinfeld, C J, Ingardia
Rok vydání:	2000
Předmět:	Fetal Diseases Pregnancy Sacrococcygeal Region Karyotyping Teratoma Humans Female Ultrasonography Prenatal
Zdroj:	Cancer genetics and cytogenetics. 117(1)
ISSN:	0165-4608
Popis:	Partial duplication of the long arm of chromosome 1 has been observed in fetal intracranial teratomas. We sonographically diagnosed a 19-week fetus with sacrococcygeal teratoma, cerebral ventriculomegaly, and cerebellar hypoplasia. Chromosomal analysis of amniocytes showed an unbalanced translocation between chromosomes 1 and 15, resulting in trisomy 1q21--1 qter. Duplication or over expression at more than one locus on the long arm of chromosome 1 may be required for the development of an extra-gonadal teratoma.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::9126219b20b33f40109d4e78429b061a https://pubmed.ncbi.nlm.nih.gov/10700874 Zobrazit plný text záznamu Full Text from ScienceDirect