[The affinity of aromatic fluoride derivatives of phenothiazine neuroleptics to spiroperidol binding sites of dopamine receptors by the radioligand technic in vitro]

Autor: W, Oelssner, G, Peinhardt, A, Büge
Jazyk: němčina
Rok vydání: 1985
Předmět:
Zdroj: Die Pharmazie. 40(5)
ISSN: 0031-7144
Popis: By introduction of fluorine into the position 7 of butaperazine, chlorpromazine, methoxypromazine, perphenazine, prochlorperazine or into the position 3 of promazine derivatives are obtained with higher affinities for the 3H-spiroperidol binding site of the dopamine receptor compared with the corresponding substances free of fluorine.
Databáze: OpenAIRE