| Autor: |
Weiss, W. R., Houghten, R. A., Good, M. F., Berzofsky, J. A., Miller, L. H., Hoffman, S. L. |
| Jazyk: |
angličtina |
| Rok vydání: |
1990 |
| Předmět: |
|
| Popis: |
Humans are infected with malaria by the bite of anophelene mosquitos carrying plasmodia sporozoites. These sporozoites pass quickly from the blood into hepatocytes, where they develop into mature liver-stage parasites over several days. The clinical stage of the illness begins only when the liver-stage parasites rupture into the bloodstream and erythrocytes are invaded. The pre-erythrocytic stages of malaria are inviting targets for vaccine development, because an effective immune response to these early stages would prevent symptomatic infections. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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