[Double-blind comparative study of slow-release ketoprofen and a placebo in chronic inflammatory rheumatism]

Autor:	J M, Harrewyn, B, Amor
Jazyk:	francouzština
Rok vydání:	1983
Předmět:	Adult Male Clinical Trials as Topic Phenylpropionates Arthritis Middle Aged Arthritis Rheumatoid Placebos Double-Blind Method Ketoprofen Delayed-Action Preparations Chronic Disease Humans Female Aged
Zdroj:	La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris. 59(46)
Popis:	Twenty-five inpatients with chronic inflammatory rheumatic disease were entered into a double blind crossover trial. Consecutive treatment regimens consisted of a single daily dose of Bi-Profenid 150 mg at 8 pm for 3 days and a single placebo tablet at 8 pm for 3 days. Order of treatment regimens was randomly assigned. Bi-Profenid proved highly superior to placebo with a very significant (p less than 0.01) difference in effectiveness on nocturnal pain, morning stiffness and pain evaluated on the pain scale. During the short treatment period no significant clinical side-effects were recorded. The authors conclude that Bi-Profenid is effective at a daily dosage of 150 mg, thus enabling to adjust prescriptions to actual needs when pain is not continuous throughout the 24 hours.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::8fe8952938df22dd6b627e14dabac678 https://pubmed.ncbi.nlm.nih.gov/6318347 Zobrazit plný text záznamu