Dynamics of pulmonary venous flow in fetuses with intrauterine growth restriction

Autor: Nathalie J M, Bravo-Valenzuela, Paulo, Zielinsky, James C, Huhta, Gregório L, Acacio, Luiz H, Nicoloso, Antonio, Piccoli, Stefano, Busato, Caroline, Klein
Rok vydání: 2014
Předmět:
Zdroj: Prenatal diagnosis. 35(3)
ISSN: 1097-0223
Popis: To test the hypothesis that the pulmonary vein pulsatility index (PVPI) is higher in fetuses with growth restriction (IUGR) than in normal fetuses.Twenty-two fetuses with IUGR and twenty-one (21) fetuses with appropriate growth for gestational age from healthy mothers were studied. PVPI was calculated by Doppler echocardiography [maximal velocity (systolic or diastolic peak) - pre-systolic peak / mean velocity]. Obstetric ultrasound was used to assess fetal biometry and Doppler to assess the uterine, umbilical and middle cerebral arteries PI. Statistical analysis used t test and Pearson's correlation.Mean gestational age was 31.5 +/- 2.1 weeks in the control group and 31.4 +/- 3.1 weeks in IUGR (P = 0.91). The PI of uterine and umbilical arteries were higher in IUGR than in controls (P 0.001). Mean PVPI in IUGR fetuses was 1.31 +/- 0.41, and in controls it was 0.83 +/- 0.11 (P 0.001).The pulsatility index of pulmonary venous flow in fetuses with growth restriction is higher than in normal fetuses, probably as a result of left atrial dynamics alteration secondary or not to fetal left ventricular diastolic dysfunction. © 2014 John WileySons, Ltd.
Databáze: OpenAIRE