Association analysis of polymorphisms in the interleukin-4 receptor (alpha) gene with atopic asthma in patients from western Mexico

Autor:	K I, Mújica-López, S E, Flores-Martínez, R, Ramos-Zepeda, S A, Castañeda-Ramos, A, Gazca-Aguilar, J, García-Pérez, J, Sánchez-Corona
Rok vydání:	2002
Předmět:	Heterozygote Polymorphism Genetic Amino Acid Substitution Humans Genetic Predisposition to Disease Interleukin-4 Immunoglobulin E Mexico Asthma Receptors Interleukin-4
Zdroj:	European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics. 29(5)
ISSN:	0960-7420
Popis:	We undertook an association analysis between the ile50val, glu375ala, cys406arg, and ser761pro polymorphisms of the IL-4Ralpha gene and atopic asthma, total IgE levels and IL-4 serum levels in a population from western Mexico. We found that the ser761pro polymorphism was monomorphic for ser761, while there was no association between any of the other polymorphisms and the three phenotypes analysed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::8f974314b1ae497288242f8665f5b047 https://pubmed.ncbi.nlm.nih.gov/12358844 Zobrazit plný text záznamu Plný text ve formátu PDF