Re-differentiation of human articular chondrocytes is not enhanced by a rotary bioreactor system

Autor: A, Barlic, N, Kregar-Velikonja
Rok vydání: 2009
Předmět:
Zdroj: Folia biologica. 54(6)
ISSN: 0015-5500
Popis: ACI is the most widely used cell-based surgical procedure for the repair of articular cartilage defects. The method is based on in vitro chondrocyte cultivation. Two different culture conditions, rotating-wall-vessel bioreactor and static culture, were assessed by their effect on the re-differentiation potential of human articular chondrocytes seeded into a hydrogel scaffold. Gene expression analysis of the tissue-engineered construct revealed no significant difference between the tested systems.
Databáze: OpenAIRE