Re-differentiation of human articular chondrocytes is not enhanced by a rotary bioreactor system
Autor: | A, Barlic, N, Kregar-Velikonja |
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Rok vydání: | 2009 |
Předmět: | |
Zdroj: | Folia biologica. 54(6) |
ISSN: | 0015-5500 |
Popis: | ACI is the most widely used cell-based surgical procedure for the repair of articular cartilage defects. The method is based on in vitro chondrocyte cultivation. Two different culture conditions, rotating-wall-vessel bioreactor and static culture, were assessed by their effect on the re-differentiation potential of human articular chondrocytes seeded into a hydrogel scaffold. Gene expression analysis of the tissue-engineered construct revealed no significant difference between the tested systems. |
Databáze: | OpenAIRE |
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