[Management and prognostic factors for 119 patients with follicular thyroid carcinoma]
| Autor: | Wen-sheng, Liu, Guo-fen, Zhang, Zhen-gang, Xu |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
Adult
Aged 80 and over Male Lung Neoplasms Adolescent Age Factors Bone Neoplasms Middle Aged Iodine Radioisotopes Survival Rate Young Adult Lymphatic Metastasis Adenocarcinoma Follicular Thyroidectomy Humans Lymph Node Excision Female Radiotherapy Adjuvant Thyroid Neoplasms Neoplasm Recurrence Local Child Aged Follow-Up Studies Neoplasm Staging Retrospective Studies |
| Zdroj: | Zhonghua zhong liu za zhi [Chinese journal of oncology]. 35(10) |
| ISSN: | 0253-3766 |
| Popis: | To explore the optimal management and analyze the prognostic factors for follicular thyroid carcinoma.The clinicopathological data of 119 patients with well-differentiated follicular thyroid carcinoma treated in our hospital from 1970 to 2008 were retrospectively reviewed. The overall survival (OS) rate was estimated by Kaplan-Meier method. Log rank and Cox regression analyses were used to identify the prognostic factors.The 5- and 10-year OS rates were 81.1% and 66.7%, respectively. The 3- , 5- and 10-year cumulative distant metastasis rates were 27.4%, 29.6% and 35.9%, respectively. The age of ≥ 45 years old was one of the most important factors affecting survival rate (P0.05) and an independent factor for distant matastasis.Follicular thyroid carcinoma has some special features such as diffuse growth and vascular tumors thrombosis and with a relatively poor prognosis. The key measure to improve local control and prognosis is radical resection. Some aggressive management such as total thyroidectomy combined with (13)1I therapy and regular follow-up should be performed to improve the survival rate and to control postoperative distant metastasis for patients ≥ 45 years old. |
| Databáze: | OpenAIRE |
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