| Autor: |
M L, McDermott, S, Vale, F, Tayfour, J W, Cowden |
| Rok vydání: |
1998 |
| Předmět: |
|
| Zdroj: |
Ophthalmic surgery and lasers. 29(10) |
| ISSN: |
1082-3069 |
| Popis: |
To determine the effect of photorefractive keratectomy (PRK) on intraocular steroid penetration.To assess steroid penetration after PRK, four rabbits underwent unilateral myopic 9.90-D PRK procedures. The other eye was left undisturbed as a control. One week later both eyes received hourly doses of radiolabeled topical dexamethasone.No significant difference in corneal tissue [(mean +/- 1 SD) PRK 4.8 +/- 1.1 micrograms/g, control 5.2 +/- 1.2 micrograms/g] or aqueous humor concentration [(mean +/- 1 SD) PRK 0.8 +/- 0.12 microgram/ml, control 0.9 +/- 0.05 microgram/ml] of dexamethasone was seen.Dexamethasone penetration in eyes 1 week following PRK is similar to that of the unablated cornea. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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