[The effect of benzofurocaine on acute inflammation in rats and on the activity of prostaglandin synthetase in vitro]

Autor:	G I, Stepaniuk, A A, Stoliarchuk, A T, Mevkh, N D, Igumnova
Rok vydání:	1990
Předmět:	Inflammation Male Diclofenac Dose-Response Relationship Drug Anti-Inflammatory Agents Non-Steroidal Drug Evaluation Preclinical Seminal Vesicles In Vitro Techniques Rats Microsomes Acute Disease Animals Edema Cyclooxygenase Inhibitors Female Anesthetics Local Benzofurans
Zdroj:	Farmakologiia i toksikologiia. 53(2)
ISSN:	0014-8318
Popis:	Benzofurocaine similarly to ortophen (voltaren) causes dose-dependent suppression of acute inflammatory reactions induced in rats by carragheenin, serotonin and histamine, protects animals from absolutely lethal dose of cellulose sulphate. When administered in a dose of 0.79 X 10(-3) M, benzofurocaine exerts no effect on the activity of prostaglandin synthetase.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::8ef697b7668cf86ea77d9494c9d62d22 https://pubmed.ncbi.nlm.nih.gov/2115012 Zobrazit plný text záznamu