Evaluation of the α-synuclein PET radiotracer (d

Autor: Nakul Ravi, Raval, Clara Aabye, Madsen, Vladimir, Shalgunov, Arafat, Nasser, Umberto Maria, Battisti, Emily Eufaula, Beaman, Morten, Juhl, Louise Møller, Jørgensen, Matthias Manfred, Herth, Hanne Demant, Hansen, Pontus, Plavén-Sigray, Gitte Moos, Knudsen
Rok vydání: 2022
Předmět:
Zdroj: Nuclear medicine and biology.
ISSN: 1872-9614
Popis: A positron emission tomography (PET) radiotracer to neuroimage α-synuclein aggregates would be a crucial addition for early diagnosis and treatment development in disorders such as Parkinson's disease, where elevated aggregate levels are a histopathological hallmark. The radiotracer (dThe α-PFF and AD homogenate injected brain regions had high uptake of (dWe find that both α-PFF and AD brain homogenates give rise to increased binding of (d
Databáze: OpenAIRE