Neuroblastoma Among Omani Children

Autor: Al-Battashi, Abeer, Al-Rahbi, Ameera, Al-Rawahi, Abdulhakeem, Mamdouh, Mohammed, Al-Ghaithi, Ibrahim, Ramadhan, Fatma A.
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Sultan Qaboos University Medical Journal
ISSN: 2075-0528
2075-051X
Popis: Objectives A limited number of publications from the Middle East have focused on neuroblastoma, a common childhood malignancy. This study describes the clinical characteristics and survival outcome of Omani children with neuroblastoma treated at the National Oncology Centre, Oman, between 2010 and 2017. Methods From January 2010 to December 2017, data on Omani children aged less than 13 years with neuroblastoma were retrospectively collected. Survival data were statistically correlated with known prognostic factors, including age, stage of disease, MYCN profile and presence of metastasis. Results A total of 56 Omani children were included. in this study. The male to female ratio was 1:1. The mean age at presentation was one year and 10 months. The two most common presenting complaints were body masses (48.2%) and constitutional symptoms (33.9%). Approximately, 54.5% were high risk, 35.7% were intermediate risk and 9.8% were low risk. High-risk neuroblastoma was mainly found in children older than one year (76.6%), with low risk mainly observed in children less than one year of age (80%). The overall survival of all groups combined was 74% (P
Databáze: OpenAIRE