| Autor: |
Vicent, Bodí, Juan, Sanchís, Antonio, Losada, Diego, García, Julio, Núñez, Mauricio, Pellicer, José, Millet, Francisco J, Chorro, Angel, Llácer |
| Rok vydání: |
2005 |
| Předmět: |
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| Zdroj: |
Revista espanola de cardiologia. 58(2) |
| ISSN: |
0300-8932 |
| Popis: |
After a myocardial infarction, damage to the microcirculation indicates a worse prognosis. We compared the usefulness of the quantitative analysis of myocardial contrast echocardiography with intravenous injection of contrast (MCE-iv) with intracoronary injection (MCE-ic) for analyzing coronary perfusion.We studied 42 patients with a first ST-elevation myocardial infarction, single-vessel disease and a patent artery (TIMI 3, stenosis50%). Myocardial perfusion in segments in the infarct-related area was quantified (normalized scale 0-1) with MCE-ic (bolus of Levovist, real-time imaging, perfusion considered normal if0.75) and MCE-iv (perfusion of SonoVue, single-image capture in 1 out of each 6 cycles with trigger set at end-systole, perfusion considered normal if0.9). Perfusion was considered abnormal if 2 or more segments showed altered perfusion.Quantification with MCE-iv took 5 +/- 1 minutes. No side effects were observed. MCE-ic was normal in 141 segments (80%) out of 176 segments included in the infarcted area, whereas 35 segments (20%) showed abnormal perfusion. MCE-ic was normal in 31 patients (74%) and was altered in 11 cases (26%). Normal perfusion with MCE-iv had a sensitivity of 91%, a specificity of 84% and a kappa index of 0.67 for predicting normal perfusion with MCE-ic (r = 0.86; P.0001 between the two techniques).In comparison with MCE-ic, quantitative analysis of single images captured during intravenous perfusion of contrast is an easy, rapid and valid method for analyzing postinfarction coronary perfusion. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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