[Simultaneous allotransplantation of the adrenal gland and the kidney]

Autor: J M, Dubernard, P, Cloix, L C, Feitosa-Tajra, F, Borson-Chazot, B, Bancel, J, Baulieux, X, Martin
Jazyk: francouzština
Rok vydání: 1996
Předmět:
Zdroj: Chirurgie; memoires de l'Academie de chirurgie. 121(3)
ISSN: 0001-4001
Popis: Thirteen months after a bilateral nephrectomy for a synchronous bilateral renal cell carcinoma involving both adrenal glands, a 46 years-old man underwent a simultaneous adrenal and kidney allotransplantation. The left renal allograft was harvested together with a ipsilateral adrenal gland using a common aortic patch. Maintenance immunosuppression was based on azathioprine, antilymphocyte globulin cyclosporine and prednisolone. Kidney allograft function remained stable for 5 years until the patient died from multifocal pancreatic metastases. Clinical, biochemical, radiological and histological arguments demonstrated the function of adrenal allograft. To our knowledge, it is the first report of a simultaneous kidney and adrenal gland allotransplantation in a therapeutic intent. An adrenal gland allotransplantation is only justified when the adrenal insufficiency exists with an end stage organ failure requiring transplantation and therefore immunosuppressive drugs.
Databáze: OpenAIRE