| Autor: |
Priya, Thomas, Pratibha, Ramani, Priya, Premkumar, Anuja, Natesan, Herald J, Sherlin, Thiruvengadam, Chandrasekar |
| Rok vydání: |
2012 |
| Předmět: |
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| Zdroj: |
Analytical and quantitative cytology and histology. 34(3) |
| Popis: |
To evaluate DNA damage and cellular death in exfoliated buccal mucosa cells from healthy individuals following dental X-ray exposure, to compare effects of different types of radiographic techniques using the buccal cytome assay and to standardize the staining procedure.This study comprised 90 patients, categorized into 3 groups subjected to intraoral periapical radiography, conventional orthopantomogram and digital orthopantomogram X-ray exposure. Exfoliated oral mucosa cells were collected immediately before the X-ray and 10 days later and stained using DNA-specific stains and nonspecific DNA stains.The results indicated no statistically significant differences in micronucleated cells before and after dental X-ray exposure. On the other hand, X-ray exposure did increase other nuclear alterations closely related to cytotoxicity, such as karyorrhexis, pyknosis and karyolysis.These data indicate that dental radiography may not induce chromosomal damage, but it is able to promote cytotoxicity. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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