| Autor: |
Jun-long, Yu, Ping, Yu, Li-xin, Li |
| Rok vydání: |
2003 |
| Předmět: |
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| Zdroj: |
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University. 28(2) |
| ISSN: |
1000-5625 |
| Popis: |
To investigate the effect of Chlamydia trachomatis serotype K infection on productions of IL-8 and IL-10 in supernatant of cultured Hela cells.The levels of IL-8 and IL-10 productions were detected by cell culture method and ELISA assay.The amount of IL-8 and IL-10 in the cell culture supernatant rose with the increasing doses of Chlamydia trachomatis. The concentrations of IL-8 and IL-10 began to increase obviously at 24 h, and reached their highest level at 72 h, and then decreased. Heat-inactivated Chlamydia trachomatis induced lower levels of IL-8 and IL-10 production than live bacteria in vitro.The Chlamydia trachomatis can induce the secretion of IL-8 and IL-10 of host cells in a dose and time dependent manner and the intracellar replication of the bacteria is required for enhancing IL-8 and IL-10 productions by the infected cells. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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