[Surgical treatment of myasthenia gravis in children]

Autor: Ia B, Iudin, O G, Kogan, Iu D, Prokopenko, I I, Klepikov, G V, Vusik, K K, Fedorov, V V, Ivanov, V A, Diupin, O S, Merzeniuk
Rok vydání: 1989
Předmět:
Zdroj: Khirurgiia. (11)
ISSN: 0023-1207
Popis: The article deals with the treatment of myasthenia in 33 children whose ages ranged from 3 to 15 years. Myasthenia of moderate severity was diagnosed in 14, severe in 15, and extremely severe in 2 children. To make a precise diagnosis, loading, neostigmine methylsulfate, cold, and D-tubocurarine tests were conducted. Thymectomy was performed in 32 patients. The operation was carried out through a T-shaped sternotomy approach. Thymogenic myasthenia was verified in 31 patients and thymomogenic only in one patient. There were no fatal outcomes. The late-term results were studied in 12 patients in follow-up periods of 3 to 6 years. Adaptational activity of the patients, anticholinesterase agents and the results of stimulant electric myography served as the criterion in appraising the late-term results. Modern diagnostic methods and surgical intervention ensure a favourable result in 75% of patients.
Databáze: OpenAIRE