Autor: |
C B, Dabbert, R L, Lochmiller, R J, Morton, K C, Powell |
Rok vydání: |
1996 |
Předmět: |
|
Zdroj: |
Avian diseases. 40(1) |
ISSN: |
0005-2086 |
Popis: |
A pathogenic challenge model causing approximately 50% mortality was developed in adult Northern bobwhite (Colinus virginianus) using Avichol, a live vaccine containing the Clemson University (CU) strain of Pasteurella multocida Type 3. A dose of 2300 or 3000 colony-forming units (CFU) of Avichol injected intramuscularly resulted in 30 to 75% mortality, whereas a dose of 230 CFU or less resulted in no mortality, and 58,720 CFU or more resulted in death in all birds challenged. Primary and secondary vaccination of Northern bobwhite with a formalinized anaculture of Avichol -derived P. multocida resulted in protection against challenge in three separate experiments. Dexamethasone treatment of birds during vaccination resulted in decreased protection against challenge exposure. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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