[In vitro methods suitable for the prediction of drug and ABC transporter, especially ABCG2 interactions]

Autor:	Akos, Pál, Emese, Kis, Dóra, Méhn, Hristos, Glavinas, Tünde, Nagy, Péter, Mészaros, György, Báthori, Péter, Krajcsi, György, Falkay
Rok vydání:	2008
Předmět:	Insecta Drug Therapy ATP Binding Cassette Transporter Subfamily G Member 2 Animals Humans ATP-Binding Cassette Transporters Biological Transport Drug Interactions Cell Line Neoplasm Proteins Xenobiotics
Zdroj:	Acta pharmaceutica Hungarica. 77(4)
ISSN:	0001-6659
Popis:	ABCG2, a transporter of the ATP-binding cassette family, is known to play a prominent role in the absorption, distribution, metabolism, and excretion of xenobiotics. Drug-transporter interactions are commonly screened by in vitro systems using transfected insect and/or human cell lines.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::8c62c30bd8c18fbfe5e25edae65a9549 https://pubmed.ncbi.nlm.nih.gov/18290540 Zobrazit plný text záznamu