Morphological and biochemical characteristics in the experimentally treated rats with indigenous synthetical products used as pesticides

Autor: G, Filipescu, E, Codorean, D, Laky, C, Tănase, L, Ciotaru
Rok vydání: 1991
Předmět:
Zdroj: Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. 37(1-2)
ISSN: 1220-0522
Popis: In acute experimental intoxication with 3 indigenous pesticides (Tripinacloraz, Lemax and Maleic Hydrazide-Na salt) the changes of some biochemical parameters, reflecting the degree of hepatic structural alterations, were studied. The pesticides were administered by gastric gavage in a single dose close to DL50 to Wistar male rats. The morphological alterations were in good correlation with a different hepatocellular levels localization. Reversible morphological lesions (granulovascuolar like dystrophy and circulatory disorders) without any pathological significance on dose-effect correlation induced a progressive response especially on serum ceruloplasmine, leucinaminopeptidase and lactatdehydrogenase.
Databáze: OpenAIRE