On the prediction of the histologic composition of benign prostatic hyperplasia based on clinical and MRI parameters

Autor:	R E, Weijers, J V, Zambon, A G, Kessels, A P, de Bruïne
Rok vydání:	1997
Předmět:	Aged 80 and over Male Models Statistical Predictive Value of Tests Prostate Prostatic Hyperplasia Humans Regression Analysis Middle Aged Magnetic Resonance Imaging Models Biological Aged Ultrasonography
Zdroj:	The Prostate. 32(3)
ISSN:	0270-4137
Popis:	The histologic composition of prostate adenoma seems related to the development of clinical benign prostatic hyperplasia (BPH). Therefore, a new noninvasive prediction model as an alternative for biopsies was investigated.In 19 patients, the data of a routine preoperative workup for transurethral resection (TURP) and of an additional MRI-examination were related to the results of morphometry on TURP-tissue.Statistical analysis identified age of the patient and MRI-volumetrics of the prostate adenoma as best predictors of the epithelial fraction, with a 95% confidence interval of at least 5% (range, 9-14%) (R2 = 50%).This prediction model is sufficiently accurate to categorize a population of patients into histologic subgroups. It seems very likely that this method will be of use as an investigative tool in medical trials to provide insight into the pathogenesis of clinical BPH and into treatment strategies for the individual patient.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::8c55664f3ada72d928d0c1596a10e9f3 https://pubmed.ncbi.nlm.nih.gov/9254897 Zobrazit plný text záznamu Plný text