Inhibition of BACE1 and Amyloid-β Aggregation by Meroterpenoids from the Mushroom

Autor: Youki, Masuda, Koji, Fujihara, Satoshi, Hayashi, Hiroaki, Sasaki, Yoshihiro, Kino, Hitoshi, Kamauchi, Masahiro, Noji, Jun-Ichi, Satoh, Toshikatsu, Takanami, Kaoru, Kinoshita, Kiyotaka, Koyama
Rok vydání: 2021
Předmět:
Zdroj: Journal of natural products. 84(6)
ISSN: 1520-6025
Popis: To develop drugs to treat Alzheimer's disease (AD) on the basis of the amyloid cascade hypothesis, the amyloid-β (Aβ) aggregation inhibitory activities of 110 extracts from mushrooms were evaluated by thioflavin T (Th-T) assays. The MeOH extract of
Databáze: OpenAIRE