| Autor: |
Masato, Nakamura, Kentarou, Maruyama, Junkou, Furukawa, Naomi, Maruyama, Junnichi, Tanaka, Yoshihiro, Katsumoto, Hideoki, Yokouchi, Kazunori, Nakaguchi, Fumiaki, Sue, Wataru, Yoshihara |
| Rok vydání: |
2002 |
| Předmět: |
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| Zdroj: |
Gan to kagaku ryoho. Cancerchemotherapy. 29(10) |
| ISSN: |
0385-0684 |
| Popis: |
Five patients with inoperable advanced gastric cancer were treated with combination chemotherapy of TS-1 and cisplatin (CDDP). TS-1 of 80-120 mg/body/day was orally administered for 3 weeks followed by 2 drug-free weeks, and 60 mg/m2/day of CDDP was venally administered on Day 8. It was possible to evaluate all 5 patients for response and toxicity. Only low grade toxicities (Grade 1 or 2) of leukocytopenia, neutrocytopenia, anemia, nausea, diarrhea and stomatitis were seen. Four of 5 patients achieved a partial response, for a response rate of 80.0%. Stomach, liver, lymph node and peritoneal tumors responded to TS-1/CDDP. TS-1/CDDP therapy produces a high response in cases of gastric cancer, and it is useful as a neoadjuvant chemotherapy. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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