[Diagnostic value of autoantibodies to asialoglycoprotein receptor in autoimmune hepatitis]

Autor: V É, Sagynbaeva, L B, Lazebnik, E V, Vinnitskaia, A S, Dorofeev, L I, Efremov
Rok vydání: 2014
Předmět:
Zdroj: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimentalclinical gastroenterology. (8)
ISSN: 1682-8658
Popis: Among 106 patients with autoimmune liver disease in 12 (11.3%) were found autoantibodies to asialoglycoprotein receptor (anti-ASGPR): in 5 (9.1%) of 55 with PBC, and 4 (17.4%) of 23 with AIH and 3 (10.7%) of 28 patients with syndrome chiasm (PBC + AIH). Detection of antibodies against the ASGPR is an effective method for diagnosis of autoimmune hepatitis. Further improvement of this method allows for monitoring and disease. Anti-ASGPR levels correlate with biochemical parameters and with the severity and manifestation autoimmune processes in patients with autoimmune hepatitis.
Databáze: OpenAIRE