[The antioxidant defense system in hypertension patients on a diet enriched with omega 3 polyunsaturated fatty acids and alpha-tocopherol]

Autor: A V, Vasil'ev, I R, Biiasheva, G R, Pokrovskaia, G Iu, Mal'tsev, E A, Varsanovich, L A, Orlova, S Kh, Soto
Rok vydání: 1994
Předmět:
Zdroj: Voprosy meditsinskoi khimii. 40(3)
ISSN: 0042-8809
Popis: A state of the anti-oxidation system in blood and the rate of lipid peroxidation were studied in patients with hypertension. High sensitivity of the anti-oxidation system enzymes to alterations in the diet fat composition was detected in the patients, nutrition of whom was evaluated in detail. Excessive doses of alpha-tocopherol, added to the diet enriched with omega 3-polyunsaturated fatty acids normalized lipid peroxidation and stabilized the enzyme activity involved in the anti-oxidation system. The integral parameter, proposed for evaluation of the anti-oxidation protection state and designated as "anti-oxidation index" involved estimation of catalase, superoxide dismutase, glutathione reductase and peroxidase activities as well as of content of malonic dialdehyde and diene conjugates in erythrocytes.
Databáze: OpenAIRE