| Autor: |
P A, Gantt, P T, Tho, V K, Bhalla, P G, McDonough, A, Costoff, V B, Mahesh |
| Rok vydání: |
1982 |
| Předmět: |
|
| Zdroj: |
The Journal of pharmacology and experimental therapeutics. 223(3) |
| ISSN: |
0022-3565 |
| Popis: |
By using pair-feeding technique, the number of gonadotropin binding sites per unit mass of testicular homogenate was measured 15, 30, 45 and 60 days after ethanol administration to 60-day-old male rats. The ingestion of ethanol (5%, v/v) as a part of a nutritionally adequate liquid diet resulted in 30, 35 and 40% reduction in gonadotropin receptors by 15, 30 and 45 days, respectively. The body weights in the alcohol-fed rats were comparable to pair-fed controls. These findings suggest that the presence of ethanol in the liquid diet depresses the level of gonadotropin receptors in the rat testis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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