| Autor: |
Michael, Walsh, Claudette, Bethune, Andrew, Smyth, Jessica, Tyrwhitt, Shiangtung W, Jung, Rosie Z, Yu, Yanfeng, Wang, Richard S, Geary, Jeffrey, Weitz, Sanjay, Bhanot |
| Rok vydání: |
2021 |
| Zdroj: |
Kidney international reports. 7(2) |
| ISSN: |
2468-0249 |
| Popis: |
Patients with end-stage renal disease (ESRD) requiring hemodialysis (HD) have an increased risk of thrombotic events and bleeding. Antisense reduction of factor XI (FXI) with IONIS-FXIThis multicenter study enrolled 49 patients receiving HD in 2 parts. First, 6 participants (pharmacokinetics [PK] cohort) received 1 open-label 300 mg dose of IONIS-FXIThe PK of IONIS-FXIIONIS-FXI |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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