[The effect of different temperature regimens in reperfusion on the recovery of myocardial contractile function after hypothermic cardiac ischemia]

Autor:	G A, Boiarinov, O V, Gorokh, M V, Balandina, I V, Mukhina
Rok vydání:	1991
Předmět:	Male Time Factors Hypothermia Induced Myocardium Cyclic AMP Temperature Animals Coronary Disease Female Myocardial Reperfusion Myocardial Contraction Rats
Zdroj:	Biulleten' eksperimental'noi biologii i meditsiny. 111(2)
ISSN:	0365-9615
Popis:	The changes of the contractile function of the heart and cAMP content in myocardium depending on the temperature conditions of reperfusion (28 degrees C, 32 degrees C, 37 degrees C) after 90 minutes of hypothermal ischemia have been investigated on isolated hearts of rats. The comparative analysis of the investigation results has shown that, after cooling a cardial muscle to 8-12 degrees C, reperfusion with initial temperature of perfusate of 32 degrees C promotes fast restoration of independent cardiac activity, does not cause formation of reperfusion contracture, normalizes processes of synthesis and cAMP utilization in cardiomyocytes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::8ab19a6f98c195d434000b5f211d646d https://pubmed.ncbi.nlm.nih.gov/1649651 Zobrazit plný text záznamu