[Pulmonary metastases in children with solid tumours--own experiences]
| Autor: | Małgorzata, Szumera, Piotr, Czauderna, Stefan, Popadiuk, Joanna, Renke, Katarzyna, Sznurkowska, Jacek, Gołebiewski, Maria, Korzon |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Osteosarcoma Carcinoma Hepatocellular Lung Neoplasms Adolescent Liver Neoplasms Bone Neoplasms Sarcoma Ewing Prognosis Neuroblastoma Treatment Outcome Carcinoma Embryonal Oncology Service Hospital Endocrine Gland Neoplasms Humans Female Poland Child Follow-Up Studies Retrospective Studies |
| Zdroj: | Medycyna wieku rozwojowego. 10(3 Pt 1) |
| Popis: | The most frequent reasons of relapses in solid tumours among children are lung metastases.Analysis of lung metastatic cases among children with solid tumours treated from 1995-2005.26 lung metastatic cases (17 males, 9 females) were analysed. At the moment of the diagnosis lung metastases were present in 19.2% of patients while in the rest (80.8%) occurred during and after treatment. The most often lung metastases were recognised in osteosarcoma (15-57.8%) and carcinoma embryonale (3-11.6%). Secondary metastases in lungs occurred within 4-48 months after the diagnosis. In 57.7% were bilateral. 36 thoracotomies (average 1.7/ a child) were performed. The after-surgery chemotherapy for tumour recurrence was introduced in each case.In the analysed group 14 (53.8%) children are alive with the overall survival time 8-120 months. The rest 12 (46.2%) are dead with the survival time 6-24 months. The statistically significant difference was found in comparison of complete surgery versus incomplete (p=0.02), no significance was found in primary or secondary metastases (p=0.27). Time of occurrence was statistically insignificant (p=0.26).The occurrence of metastases in children solid tumours worsened the prognosis. The active search for lung metastases at the moment of diagnosis, treatment and follow-up combined with complete surgery procedures may prolong survival. There is a need to find new methods of lung metastases treatment. |
| Databáze: | OpenAIRE |
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