[Experience with using aclarubicin in the treatment of acute leukemia and blast crisis of chronic myeloid leukemia]
| Autor: | V G, Savchenko, V G, Isaev, E M, Abakumov, N D, Khoroshko, A G, Turkina, A N, Sokolov, M M, Viadro, S M, Navashin |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
Adult
Leukemia Remission Induction Cytarabine Middle Aged Precursor Cell Lymphoblastic Leukemia-Lymphoma Leukemia Myelomonocytic Acute Leukemia Myeloid Acute Leukemia Myelogenous Chronic BCR-ABL Positive Antineoplastic Combined Chemotherapy Protocols Leukemia Monocytic Acute Humans Aclarubicin Blast Crisis Aged |
| Zdroj: | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]. 37(7) |
| ISSN: | 0235-2990 |
| Popis: | The clinical efficacy of aclarubicin, an anthracycline antibiotic, was studied in 48 patients with leukemia. The antibiotic was used in the following combinations with cytarabine: "7 + 7", "5 + 5" and "73". A complete remission was stated in 14 (42.4 per cent) out of 33 patients with acute nonlymphoid leukemia, 6 (43 per cent) out of the 14 patients having relapses. The combined therapy was effective in 4 out of 5 pre-resistant patients. The "7 + 3" scheme was the most beneficial. The most common adverse reactions were nausea and vomiting. |
| Databáze: | OpenAIRE |
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