Morphogenetic Aspects of the Response of Vaginal Tissues to Polypropylene Implants as the Basis of Mesh-Associated Complications

Autor:	I A, Eisenach, A K, Pichigina, G A, Lapii, V G, Mozes
Rok vydání:	2020
Předmět:	Mucous Membrane Macrophages Urinary Incontinence Stress Prostheses and Implants Fibroblasts Middle Aged Surgical Mesh Polypropylenes Immunohistochemistry Pelvic Organ Prolapse Postoperative Complications Vagina Leukocytes Humans Female Aged
Zdroj:	Bulletin of experimental biology and medicine. 171(2)
ISSN:	1573-8221
Popis:	Morphometric and immunohistochemical examination of the vaginal mucosa before and 12 months after installation of polypropylene implants for the correction of stress urinary incontinence was performed in 20 patients with genital prolapse. The research results confirmed good biocompatibility of polypropylene and the formation of full-fledged connective tissue in the vaginal mucosa, but revealed the presence of a weak lymphocytic reaction to polypropylene 12 months after surgery. According to immunohistochemical study, increased contents of B lymphocytes and plasma cells responsible for the inductive and productive stages of the immune response were revealed in the vaginal mucosa around the implants 12 months after surgery. This reaction in the presences of provoking factors can lead to the development of inflammation and erosion, a type of mesh-associated complications.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::88fdf601ae352a3669715f73e3786813 https://pubmed.ncbi.nlm.nih.gov/34173111 Zobrazit plný text záznamu Full text from SpringerLink