| Autor: |
F, Kryukov, E, Dementyeva, P, Kuglík, R, Hájek |
| Rok vydání: |
2011 |
| Předmět: |
|
| Zdroj: |
Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti. |
| ISSN: |
0862-495X |
| Popis: |
The presence of multiple centrosomes in tumor cells is associated with the formation of multipolar mitotic spindles and results in aneuploidy of both daughter cells. Centrosome amplification is a feature of all cancer cells. We have previously described centrosome amplification in abnormal B cells. Further studies of centrosome amplification in different stages of B lineage development could provide important information about multiple myeloma pathogenesis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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