| Autor: |
Igor, Olaciregui-Ruiz, Julia-Maria, Osinga-Blaettermann, Karen, Ortega-Marin, Ben, Mijnheer, Anton, Mans |
| Rok vydání: |
2021 |
| Zdroj: |
Physics and imaging in radiation oncology. 22 |
| ISSN: |
2405-6316 |
| Popis: |
EPID_IA dose distributions were converted into patient dose distributions (EPID_IA_MC) by applying a 3D dose inhomogeneity conversion, defined as the ratio between patient and water-filled patient dose distributions computed using Monte Carlo calculations. EPID_IA_MC was evaluated against dose distributions calculated with a collapsed cone convolution superposition (CCCS) algorithm and with a GPU-based Monte Carlo dose calculation platform (GPUMCD) using non-transit EPID measurements of 25 plans.In the evaluation of EPID_IA_MC, the average γ-mean values (2% local/2mm, 50% isodose volume) were 0.70 ± 0.14 (1SD) and 0.66 ± 0.10 (1SD) against CCCS and GPUMCD, respectively. Percentage differences in median dose to the planning target volume were within 3.9% and 2.7%, respectively. The number ofEPID_IA_MC accommodates accurate patient dose reconstruction for treatment disease sites with significant tissue inhomogeneities within a simple EPID-based direct dose back-projection algorithm, and helps to improve the clinical interpretation of both pre-treatment and |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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