[Study of certain indicators of immunity upon infecting CBA/Calac line mice with Lassa virus]

Autor: G M, Ignat'ev, S A, Kaliberov, L A, Pereboeva, A B, Tverdokhlebov, A G, Kras'ko, A T, Godneva
Rok vydání: 1994
Předmět:
Zdroj: Voprosy virusologii. 39(6)
ISSN: 0507-4088
Popis: Some immunity parameters (interferon, tumor necrosis factor, interleukin 1, etc.) were studied in CBA/Calac mice infected with Lassa virus. The results permit a hypothesis that a pathologic inflammatory reaction is responsible for the death of animals in experimental Lassa fever. One of the components of this reaction is endogenous shock involving a manifest production of immune response mediators, such as interferon, interleukin 1. and tumor necrosis factor.
Databáze: OpenAIRE