Psoriasin: key molecule of the cutaneous barrier?

Autor:	Regine, Gläser, Bente, Köten, Maike, Wittersheim, Jürgen, Harder
Jazyk:	němčina
Rok vydání:	2011
Předmět:	Keratinocytes Skin Neoplasms Skin Absorption S100 Proteins Skin Diseases S100 Calcium Binding Protein A7 Gene Expression Regulation Neoplastic Immunomodulation Anti-Infective Agents Neoplasms Humans Psoriasis Wounds and Injuries Skin
Zdroj:	Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG. 9(11)
ISSN:	1610-0387
Popis:	Psoriasin (S100 A7) was discovered two decades ago as a protein abundantly expressed in psoriatic keratinocytes. Even though much scientific research has been carried out on the characterization of psoriasin, only recent studies point to an important role of psoriasin as an antimicrobial and immunomodulatory protein in skin and other epithelia. In this review, we provide an overview of the major findings in psoriasin research and discuss novel studies highlighting the role of psoriasin as an important effector molecule of the cutaneous barrier.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::88aaab75b3b4b35b37d63e7b2b2236b7 https://pubmed.ncbi.nlm.nih.gov/21501383 Zobrazit plný text záznamu Plný text