[The mechanisms of the formation of heterologous resistance in peroral immunization with a complex anti-influenza preparation]

Autor:	N A, Markevich, I I, Maslennikova, E E, Pokrovskaia, M V, Osipova, A V, Ispolatova
Rok vydání:	1996
Předmět:	Male Interferon Inducers beta-Glucans Drug Evaluation Preclinical Administration Oral Immunity Innate Drug Combinations Mice Orthomyxoviridae Infections Vaccines Inactivated Influenza A virus Influenza Vaccines Animals Immunization Glucans
Zdroj:	Vestnik Rossiiskoi akademii meditsinskikh nauk. (1)
ISSN:	0869-6047
Popis:	The paper presents experimental findings of the combined antiinfluenza drug (inactivated influenza vaccine + an interferon inducer - an immunogenetic anstimulator - polysaccharide 1,3beta-glucan). The oral immunization with the drug induces antibody accumulation in the secretions of the upper airway and blood sera in defense titers, interferon synthesis at days 1-3 postadministration, forms murine resistance to infection with homologous and heterologous viruses, enhances the functional activity of alveolar macrophages.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::88a66bb57bfc512f86c196f9f5985209 https://pubmed.ncbi.nlm.nih.gov/8907427 Zobrazit plný text záznamu