Retroviral glycoprotein-mediated immune suppression via the potassium channel K

Autor:	Magdalena J, Laska, Jesper Bonnet, Moeller, Jonas Heilskov, Graversen, Dorte, Strøbæk, Linda, Blomster, Palle, Christophersen, Shervin, Bahrami
Rok vydání:	2022
Předmět:	Disease Models Animal Mice Tumor Necrosis Factor-alpha Potassium Channel Blockers Animals Humans Colitis Inflammatory Bowel Diseases Intermediate-Conductance Calcium-Activated Potassium Channels
Zdroj:	Clinical immunology (Orlando, Fla.). 242
ISSN:	1521-7035
Popis:	Peptides derived from retroviral envelope proteins have been shown to possess a wide range of immunosuppressive and anti-inflammatory activities. We have previously reported identification of such a peptide derived from the envelope protein coded by a human endogenous retrovirus (HERV). In this study, we identify that in vitro the peptide inhibits the K
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::8866e2db451294bf0a42171d5b79f15f https://pubmed.ncbi.nlm.nih.gov/35905828 Zobrazit plný text záznamu Full Text from ScienceDirect