| Autor: |
Zhi-Guo, Shan, Yong-Liang, Zhao, Jin-Yu, Zhang, Zong-Bao, Yan, Ting-Ting, Wang, Fang-Yuan, Mao, Yong-Sheng, Teng, Liu-Sheng, Peng, Wan-Yan, Chen, Pan, Wang, Ping, Cheng, Wen-Qing, Tian, Jun, Chen, Weisan, Chen, Yuan, Zhuang |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Advanced science (Weinheim, Baden-Wurttemberg, Germany). 9(5) |
| ISSN: |
2198-3844 |
| Popis: |
Neutrophils constitute abundant cellular components in human gastric cancer (GC) tissues, but their protumorigenic subset in pathogenesis of GC progression is unclear. Here, it is found that patients with GC show significantly higher neutrophil infiltration in tumors that is regulated by CXCL12-CXCR4 chemotaxis. These tumor-infiltrating neutrophils express high level immunosuppressive molecules FasL and PD-L2, and this FasL |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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