Stereoselective synthesis of Z-alpha-aryl-alpha,beta-unsaturated esters

Autor: Neelakandha S, Mani, Christopher M, Mapes, Jiejun, Wu, Xiaohu, Deng, Todd K, Jones
Rok vydání: 2006
Předmět:
Zdroj: The Journal of organic chemistry. 71(13)
ISSN: 0022-3263
Popis: An efficient method for the stereoselective synthesis of (Z)-alpha-arylacrylates is described. Treatment of alpha-hydroxyesters with triflic anhydride and pyridine at 0 degrees C followed by warming to room temperature afforded the corresponding (Z)-alpha-aryl-alpha,beta-unsaturated esters in very good yields and excellent stereoselectivity.
Databáze: OpenAIRE