Interplay between mineral bone disorder and cardiac damage in acute kidney injury: from Ca

Autor: Laura, González-Lafuente, José Alberto, Navarro-García, Elena, Rodríguez-Sánchez, Jennifer, Aceves-Ripoll, Jonay, Poveda, Sara, Vázquez-Sánchez, Elisa, Mercado-García, María, Fernández-Velasco, Makoto, Kuro-O, Fernando, Liaño, Luis M, Ruilope, Gema, Ruiz-Hurtado
Rok vydání: 2021
Předmět:
Zdroj: Translational research : the journal of laboratory and clinical medicine. 243
ISSN: 1878-1810
Popis: Biomarkers of mineral bone disorders (MBD) including phosphorus, fibroblast growth factor (FGF)-23 and Klotho are strongly altered in patients with acute kidney injury (AKI) who have high cardiac outcomes and mortality rates. However, the crosslink between MBD and cardiac damage after an AKI episode still remains unclear. We tested MBD and cardiac biomarkers in an experimental AKI model after 24 or 72 hours of folic acid injection and we analyzed structural cardiac remodeling, intracellular calcium (Ca
Databáze: OpenAIRE