Gamma-pyrone derivatives, kojic acid methyl ethers from a marine-derived fungus Alternaria [correction of Altenaria] sp

Autor: Xifeng, Li, Jee Hean, Jeong, Kang Tae, Lee, Jung Rae, Rho, Hong Dae, Choi, Jung Sook, Kang, Byeng Wha, Son
Rok vydání: 2003
Předmět:
Zdroj: Archives of pharmacal research. 26(7)
ISSN: 0253-6269
Popis: Kojic acid dimethyl ether (1), and the known kojic acid monomethyl ether (2), kojic acid (3) and phomaligol A (4) have been isolated from the organic extract of the broth of the marine-derived fungus Alternaria sp. collected from the surface of the marine green alga Ulva pertusa. The structures were assigned on the basis of comprehensive spectroscopic analyses. Each isolate was tested for its tyrosinase inhibitory activity. Kojic acid (3) was found to have significant tyrosinase inhibitory activity, but compounds 1, 2, and 4 were found to be inactive.
Databáze: OpenAIRE