Total energy expenditure is comparable between patients with and without diabetes mellitus: Clinical Evaluation of Energy Requirements in Patients with Diabetes Mellitus (CLEVER-DM) Study
Autor: | Morino, Katsutaro, Kondo, Keiko, Tanaka, Shigeho, Nishida, Yuki, Nakae, Satoshi, Yamada, Yosuke, Ugi, Satoshi, Fuse, Keiko, Miyazawa, Itsuko, Ohi, Akiko, Nishida, Kaori, Kurihara, Mika, Sasaki, Masaya, Ebine, Naoyuki, Sasaki, Satoshi, Katsukawa, Fuminori, Maegawa, Hiroshi |
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Jazyk: | angličtina |
Rok vydání: | 2019 |
Předmět: | |
Zdroj: | BMJ Open Diabetes Research & Care |
ISSN: | 2052-4897 0000-2305 |
Popis: | Objective Assessment of total energy expenditure (TEE) is essential for appropriate recommendations regarding dietary intake and physical activity in patients with and without diabetes mellitus (DM). However, few reports have focused on TEE in patients with DM, particularly in Asian countries. Therefore, we evaluated TEE in Japanese patients with DM using the doubly labeled water (DLW) method and physical activity level (PAL). Research design and methods In this cross-sectional observational study, we evaluated 52 patients with type 2 DM and 15 patients without DM. Free-living TEE was measured over 12–16 days by the DLW method, and PAL was calculated as TEE divided by the basal metabolic rate (BMR) as assessed by indirect calorimetry. The equivalence margin was defined as 5 kcal/kg/day. Results The numbers of patients with DM treated with insulin, oral antidiabetic drugs, and diet were 18 (34.6%), 20 (38.5%), and 14 (26.9%), respectively. The mean±SD level of glycated hemoglobin was 6.9%±0.8% and 5.5%±0.3% in the DM and non-DM group, respectively (p |
Databáze: | OpenAIRE |
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