| Autor: |
Maria, Adamopoulou, Dimitrios, Avgoustidis, Chrysa, Voyiatjaki, Apostolos, Beloukas, Christos, Yapijakis, Evangelos, Tsiambas, Ekatherina, Charvalos |
| Rok vydání: |
2021 |
| Předmět: |
|
| Zdroj: |
Journal of B.U.ON. : official journal of the Balkan Union of Oncology. 26(4) |
| ISSN: |
2241-6293 |
| Popis: |
The concurrent prevalence investigation of human papillomavirus (HPV), Mycoplasma hominis (Mh) and Ureaplasma urealyticum (Uu) in women in order to estimate the association of co-infection with cervical lesions.The study cohort comprised 120 women with no cervical lesions (control group) and 62 women with abnormal cytological findings from the cervix (cervical intraepithelial lesion/neoplasia) as study group. A combination of molecular analyses was implemented.The presence of HPV infection was shown in 52/62 (83.9%) of women with abnormal cytology. Women with cervix cytological findings were shown to have 17.6 times higher risk for Mh and Uu co-infection (p=0.001). HPV and Uu co-infection were detected with a higher prevalence among women with CIN 3 and invasive cancer.These findings are consistent with the notion that microbial co-infections may play an important role in persistent inflammation and progression of cervical lesions. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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