A procedure for the preparation of GM3 ganglioside from GM1-lactone

Autor:	L, Mauri, R, Casellato, G, Kirschner, S, Sonnino
Rok vydání:	1999
Předmět:	Magnetic Resonance Spectroscopy Hydrolysis Animals G(M3) Ganglioside Cattle Chromatography Thin Layer G(M1) Ganglioside Chromatography DEAE-Cellulose
Zdroj:	Glycoconjugate journal. 16(3)
ISSN:	0282-0080
Popis:	A simple procedure is described for preparing GM3 ganglioside, from a few milligrams to grams, from GM1-lactone (Sonnino et al., (1985) Glycoconjugate J 2: 343-54) [1]. The synthesis was carried out under the following optimal conditions: 30 mM GM1-lactone in 0.25 M H2SO4 in DMSO, 30 min, 70 degrees C, nitrogen atmosphere, strong stirring. The yield of GM3 was 55%. The procedure applied to milligram amounts of GD1b-dilactone gave GD3 ganglioside.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::86eb239a8260b860ff2499a7eb092d9e https://pubmed.ncbi.nlm.nih.gov/10596894 Zobrazit plný text záznamu Full text from SpringerLink