Neurological soft signs in never-treated schizophrenia

Autor: G, Venkatasubramanian, V, Latha, B N, Gangadhar, N, Janakiramaiah, D K, Subbakrishna, P N, Jayakumar, M S, Keshavan
Rok vydání: 2003
Předmět:
Zdroj: Acta psychiatrica Scandinavica. 108(2)
ISSN: 0001-690X
Popis: Studies of Neurological Soft Signs (NSS) in schizophrenia are confounded by handedness, inconsistent methodology, and prior treatment with neuroleptics. The study objective is to examine NSS in never-treated schizophrenia.We examined the NSS in treatment-naïve schizophrenia patients (n = 21) and age, sex, education, and handedness matched normal controls (n = 21) using the modified Neurological Evaluation Scale with good inter-rater reliability.Schizophrenia patients had significantly more NSS than normals. No significant correlation was found between illness duration and NSS.Higher neurological signs in never-treated patients and their lack of association with illness duration suggest neurodevelopmental etiopathogenesis of schizophrenia.
Databáze: OpenAIRE