[Two Cases of Resectable Gastric Cancer with Extensive Nodal Metastasis That Received Preoperative DOS Therapy]

Autor: Noriko, Wada, Yusuke, Akamaru, Takahiro, Shimaoka, Soichiro, Harada, Satoshi, Eguchi, Ryo, Ikeshima, Koji, Munakata, Daisuke, Takiuchi, Naoki, Hama, Hirofumi, Ota, Hiroshi, Ohashi, Kunitaka, Shibata
Rok vydání: 2022
Předmět:
Zdroj: Gan to kagaku ryoho. Cancerchemotherapy. 48(13)
ISSN: 0385-0684
Popis: Case 1: A 67-year-old male had a type 1 tumor in the stomach with a lymph node metastasis 50 mm in size. He was diagnosed with cT4aN(+)M0, cStage Ⅲ and received preoperative docetaxel plus oxaliplatin plus S-1(DOS)therapy. After 3 courses of the regimen, the patient underwent laparoscopic total gastrectomy. The final stage was ypT3N1(1/38) M0, ypStage ⅡB, R0, and the pathological response was Grade 2b. Case 2: A 64-year-old male had a type 3 tumor in the abdominal esophagus and a lymph node metastasis 15 mm in size. He was diagnosed with cT3N(+)M0, cStage Ⅲ and received preoperative DOS therapy. After 3 courses, he underwent laparoscopic esophagectomy. The final stage was ypT0N0M0, ypStage 0, R0, and the pathological response was Grade 3. DOS therapy may be effective as a neoadjuvant chemotherapy.
Databáze: OpenAIRE