| Autor: |
M G, Martinez de Haas, P J, Poels, C J, de Weert, C M, Thomas, J M, Rooyackers, W H, Hoefnagels |
| Jazyk: |
Dutch; Flemish |
| Rok vydání: |
1998 |
| Předmět: |
|
| Zdroj: |
Nederlands tijdschrift voor geneeskunde. 141(45) |
| ISSN: |
0028-2162 |
| Popis: |
To study the effect of theophylline use on the vitamin B-6 status.Descriptive.Department of Geriatric Medicine of Nijmegen Academic Hospital and Department of Pulmonary Diseases, University of Nijmegen, the Netherlands.Vitamin B-6 status was determined by measuring pyridoxal-5'-phosphate (PLP) in whole blood (using a high performance liquid chromatography method, reference values: 35-107 mumol/l) in 141 patients from the Geriatric department (84 non-chronic obstructive pulmonary disease (COPD), 40 COPD patients without theophylline and 17 COPD patients with theophylline) and in 25 non-geriatric COPD patients on theophylline.Of the 84 geriatric non-COPD patients (mean age: 82 years; SD: 6) 56% had a subnormal vitamin B-6 status, of the 40 geriatric COPD patients without theophylline (82 years; SD: 6) 70%, of the 17 geriatric COPD patients on theophylline (80 years; SD: 5) 94% and of the 25 non-geriatric COPD patients on theophylline (62 years; SD: 11) 96%.In patients who used theophylline a higher prevalence of subnormal vitamin B-6 status was found than in patients who did not. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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