E2

Autor:	Sana, Zahid, Mehreen, Gul, Shagufta, Shafique, Sajid, Rashid
Rok vydání:	2022
Předmět:	Binding Sites Endosomal Sorting Complexes Required for Transport SARS-CoV-2 Ubiquitin Ubiquitin-Protein Ligases COVID-19 Humans Nerve Tissue Proteins Ligands Peptides Protein Binding
Zdroj:	Computers in biology and medicine. 146
ISSN:	1879-0534
Popis:	Homologous to E6AP carboxyl-terminus (HECT)-type E3 ligase performs ubiquitin (Ub)-proteasomal protein degradation via forming a complex with E2∼Ub. Enveloped viruses including SARS-CoV-2 escape from the infected cells by harnessing the E-class vacuolar protein-sorting (ESCRT) machinery and mimic the cellular system through PPAY motif-based linking to HECT Ub ligase activity. In the present study, we have characterized the binding pattern of E2
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::86432de98e3c2c86fabe53e4f99a24fe https://pubmed.ncbi.nlm.nih.gov/35751189 Zobrazit plný text záznamu Full Text from ScienceDirect