| Autor: |
J L, Vivanco Martínez, A, López Panero, C, Melero Moreno, J, López Pérez |
| Rok vydání: |
1993 |
| Předmět: |
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| Zdroj: |
Anales espanoles de pediatria. 38(3) |
| ISSN: |
0302-4342 |
| Popis: |
In this study we compare two different therapies for the treatment of non-B acute lymphoblastic leukemia (ALL). Forty-four children diagnosed as having non-B ALL were treated by one of two methods: 20 children were treated from 1981 to 1984 according to the PETHEMA 7/78 protocol and 24 children were treated from 1984 to 1987 following the BFM 83 protocol. These treatments differ in that BFM 83 includes a higher number of cytostatics, uses intravenous methotrexate at moderate doses as "reservoirs" treatment and a lower dose of holocranial radiotherapy. The BFM 83 treatment resulted in a significant improvement in survival (48% versus 92% p0.05), as well as in the absence of further events (45% versus 88%, p0.01). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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