Popis: |
To assess the correlation between metformin and risk of developing lung cancer by meta-analysis.Papers on the correlation between metformin and risk of lung cancer were searched from PubMed, MEDLINE, EMBASE, ISI Web of Science, and Cochrane Library.Six papers on case-control study were included in this study, involving 39,787 metformin users and 177,752 controls. Meta-analysis showed that the risk of developing lung cancer was lower in metformin users than in those without metformin (OR=0.55, 95% CI: 0.35-0.85, P0.001).The risk of developing lung cancer is lower in metformin users than in those without metformin. |